Research and Education

 

 


I have a strong academic interest and have published a large number of scientific papers, book chapters, scientific reviews and abstracts. I have strong research collaborations with different European surgical centres. I believe that there is a serious need for continuous scientific research to improve results in the treatment of Hepatobiliary-pancreatic diseases and I hope that the coming years will see significant improvement in terms of results and prognosis. I strongly feel that every clinician is ethically and professional expected to participate to the development of evidence based medicine through clinical and experiment research. I will always offer my patients the best treatment based on the strongest scientific evidence on which I am continuously updated.

 

 

 

 

 

 

 

Research papers Written (co-author) by Mr Hilal.

 

 

 

• Wakabayashi G, Cherqui D, Geller DA, Buell JF, Kaneko H, Han HS, Asbun H, O'Rourke N, Tanabe M, Koffron AJ, Tsung A, Soubrane O, Machado MA, Gayet B, Troisi RI, Pessaux P, Van Dam RM, Scatton O, Abu Hilal M, Belli G, Kwon CH, Edwin B, Choi GH, Aldrighetti LA, Cai X, Cleary S, Chen KH, Schon MR, Sugioka A, Tang CN, Herman P, Pekolj J, Chen XP, Dagher I, Jarnagin W, Yamamoto M, Strong R, Jagannath P, Lo CM, Clavien PA, Kokudo N, Barkun J, Strasberg SM. Recommendations for laparoscopic liver resection: a report from the second international consensus conference held in Morioka. Ann Surg. 2015;261:619-29.

• Solaini L, Jamieson NB, Metcalfe M, Abu Hilal M, Soonawalla Z, Davidson BR, McKay C, Kocher HM, Group UKDCS. Outcome after surgical resection for duodenal adenocarcinoma in the UK. Br J Surg. 2015;102:676-81.

• Shelat VG, Cipriani F, Basseres T, Armstrong TH, Takhar AS, Pearce NW, AbuHilal M. Pure laparoscopic liver resection for large malignant tumors: does size matter? Ann Surg Oncol. 2015;22:1288-93.

• Roberts KJ, Sutcliffe RP, Marudanayagam R, Hodson J, Isaac J, Muiesan P, Navarro A, Patel K, Jah A, Napetti S, Adair A, Lazaridis S, Prachalias A, Shingler G, Al-Sarireh B, Storey R, Smith AM, Shah N, Fusai G, Ahmed J, Abu Hilal M, Mirza DF. Scoring System to Predict Pancreatic Fistula After Pancreaticoduodenectomy: A UK Multicenter Study. Ann Surg. 2015.

• Richardson J, Di Fabio F, Clarke H, Bajalan M, Davids J, Abu Hilal M. Implementation of enhanced recovery programme for laparoscopic distal pancreatectomy: feasibility, safety and cost analysis. Pancreatology : official journal of the International Association of Pancreatology. 2015;15:185-90.

• Di Fabio F, Barkhatov L, Bonadio I, Dimovska E, Fretland AA, Pearce NW, Troisi RI, Edwin B, Abu Hilal M. The impact of laparoscopic versus open colorectal cancer surgery on subsequent laparoscopic resection of liver metastases: A multicenter study. Surgery. 2015;157:1046-54.

• Coles SR, Besselink MG, Serin KR, Alsaati H, Di Gioia P, Samim M, Pearce NW, Abu Hilal M. Total laparoscopic management of lesions involving liver segment 7. Surg Endosc. 2015.

• Cipriani F, Shelat VG, Rawashdeh M, Francone E, Aldrighetti L, Takhar A, Armstrong T, Pearce NW, Abu Hilal M. Laparoscopic Parenchymal-Sparing Resections for Nonperipheral Liver Lesions, the Diamond Technique: Technical Aspects, Clinical Outcomes, and Oncologic Efficiency. J Am Coll Surg. 2015.

• Shelat VG, Serin K, Samim M, Besselink MG, Al Saati H, Gioia PD, Pearce NW, Abu Hilal M. Outcomes of repeat laparoscopic liver resection compared to the primary resection. World J Surg. 2014;38:3175-80.

• Shelat VG, Cipriani F, Basseres T, Armstrong TH, Takhar AS, Pearce NW, Abu Hilal M. Erratum to: Pure Laparoscopic Liver Resection for Large Malignant Tumors: Does Size Matter? Ann Surg Oncol. 2014.

• Ravikumar R, Sabin C, Abu Hilal M, Bramhall S, White S, Wigmore S, Imber CJ, Fusai G, Group UKVRiPCS. Portal vein resection in borderline resectable pancreatic cancer: a United Kingdom multicenter study. J Am Coll Surg. 2014;218:401-11.

• El-Kholy TA, Abu Hilal M, Al-Abbadi HA, Serafi AS, Al-Ghamdi AK, Sobhy HM, Richardson JR. The effect of extra virgin olive oil and soybean on DNA, cytogenicity and some antioxidant enzymes in rats. Nutrients. 2014;6:2376-86.

• Di Fabio F, Samim M, Di Gioia P, Godeseth R, Pearce NW, Abu Hilal M. Laparoscopic major hepatectomies: clinical outcomes and classification. World J Surg. 2014;38:3169-74.

• Dagher I, Gayet B, Tzanis D, Tranchart H, Fuks D, Soubrane O, Han HS, Kim KH, Cherqui D, O'Rourke N, Troisi RI, Aldrighetti L, Bjorn E, Abu Hilal M, Belli G, Kaneko H, Jarnagin WR, Lin C, Pekolj J, Buell JF, Wakabayashi G. International experience for laparoscopic major liver resection. J Hepatobiliary Pancreat Sci. 2014;21:732-6.

• Cawich SO, Johnson PB, Shah S, Roberts P, Arthurs M, Murphy T, Bonadie KO, Crandon IW, Harding HE, Abu Hilal M, Pearce NW. Overcoming obstacles to establish a multidisciplinary team approach to hepatobiliary diseases: a working model in a Caribbean setting. J Multidiscip Healthc. 2014;7:227-30.

• Tzanis D, Shivathirthan N, Laurent A, Abu Hilal M, Soubrane O, Kazaryan AM, Ettore GM, Van Dam RM, Lainas P, Tranchart H, Edwin B, Belli G, Campos RR, Pearce N, Gayet B, Dagher I. European experience of laparoscopic major hepatectomy. J Hepatobiliary Pancreat Sci. 2013;20:120-4.

• Abu Hilal M, Takhar AS. Laparoscopic left pancreatectomy: current concepts. Pancreatology : official journal of the International Association of Pancreatology. 2013;13:443-8.

• Abu Hilal M, Layfield DM, Di Fabio F, Arregui-Fresneda I, Panagiotopoulou IG, Armstrong TH, Pearce NW, Johnson CD. Postoperative chyle leak after major pancreatic resections in patients who receive enteral feed: risk factors and management options. World J Surg. 2013;37:2918-26.

• Abu Hilal M, Di Fabio F, Syed S, Wiltshire R, Dimovska E, Turner D, Primrose JN, Pearce NW. Assessment of the financial implications for laparoscopic liver surgery: a single-centre UK cost analysis for minor and major hepatectomy. Surg Endosc. 2013;27:2542-50.

• Abu Hilal M, Di Fabio F, Badran A, Alsaati H, Clarke H, Fecher I, Armstrong TH, Johnson CD, Pearce NW. Implementation of enhanced recovery programme after pancreatoduodenectomy: a single-centre UK pilot study. Pancreatology : official journal of the International Association of Pancreatology. 2013;13:58-62.

• van Dam RM, Wong-Lun-Hing EM, van Breukelen GJ, Stoot JH, van der Vorst JR, Bemelmans MH, Olde Damink SW, Lassen K, Dejong CH, Group OIS. Open versus laparoscopic left lateral hepatic sectionectomy within an enhanced recovery ERAS(R) programme (ORANGE II-trial): study protocol for a randomised controlled trial. Trials. 2012;13:54.

• Di Fabio F, Whistance R, Rahman S, Primrose JN, Pearce NW, Abu Hilal M. Exploring the role of laparoscopic surgery in two-stage hepatectomy for bilobar colorectal liver metastases. Journal of laparoendoscopic & advanced surgical techniques. Part A. 2012;22:647-50.

• Dellinger EP, Forsmark CE, Layer P, Levy P, Maravi-Poma E, Petrov MS, Shimosegawa T, Siriwardena AK, Uomo G, Whitcomb DC, Windsor JA, Pancreatitis Across Nations Clinical R, Education A. Determinant-based classification of acute pancreatitis severity: an international multidisciplinary consultation. Ann Surg. 2012;256:875-80.

• Abu Hilal M, Hamdan M, Di Fabio F, Pearce NW, Johnson CD. Laparoscopic versus open distal pancreatectomy: a clinical and cost-effectiveness study. Surg Endosc. 2012;26:1670-4.

• Abu Hilal M, Di Fabio F, Abu Salameh M, Pearce NW. Oncological efficiency analysis of laparoscopic liver resection for primary and metastatic cancer: a single-center UK experience. Arch Surg. 2012;147:42-8.

• Pearce NW, Di Fabio F, Teng MJ, Syed S, Primrose JN, Abu Hilal M. Laparoscopic right hepatectomy: a challenging, but feasible, safe and efficient procedure. American journal of surgery. 2011;202:e52-8.

• Pearce NW, Di Fabio F, Abu Hilal M. Laparoscopic left hepatectomy with extraparenchymal inflow control. J Am Coll Surg. 2011;213:e23-7.

• Mirnezami R, Mirnezami AH, Chandrakumaran K, Abu Hilal M, Pearce NW, Primrose JN, Sutcliffe RP. Short- and long-term outcomes after laparoscopic and open hepatic resection: systematic review and meta-analysis. HPB (Oxford). 2011;13:295-308.

• Di Fabio F, Abu Hilal M, Johnson CD. Acute pancreatitis: mild, severe or potentially fatal. Pancreatology : official journal of the International Association of Pancreatology. 2011;11:373-5.

• Cavallini A, Butturini G, Malleo G, Bertuzzo F, Angelini G, Abu Hilal M, Pederzoli P, Bassi C. Endoscopic transmural drainage of pseudocysts associated with pancreatic resections or pancreatitis: a comparative study. Surg Endosc. 2011;25:1518-25.

• Abu Hilal M, El Ghoul W, Zeidan S, Scio A, Di Fabio F. Laparoscopic multivisceral resection for infiltrating primary pancreatic non-hodgkin's lymphoma mimicking a vast cystic neoplasm. Am Surg. 2011;77:E212-3.

• Abu Hilal M, Di Fabio F, Wiltshire RD, Hamdan M, Layfield DM, Pearce NW. Laparoscopic liver resection for hepatocellular adenoma. World J Gastrointest Surg. 2011;3:101-5.

• Abu Hilal M, Di Fabio F, Teng MJ, Lykoudis P, Primrose JN, Pearce NW. Single-centre comparative study of laparoscopic versus open right hepatectomy. J Gastrointest Surg. 2011;15:818-23.

• Abu Hilal M, Di Fabio F, Teng MJ, Godfrey DA, Primrose JN, Pearce NW. Surgical management of benign and indeterminate hepatic lesions in the era of laparoscopic liver surgery. Dig Surg. 2011;28:232-6.

• Abu Hilal M, Badran A, Di Fabio F, Pearce NW. Pure laparoscopic en bloc left hemihepatectomy and caudate lobe resection in patients with intrahepatic cholangiocarcinoma. Journal of laparoendoscopic & advanced surgical techniques. Part A. 2011;21:845-9.

• Jain G, Parmar J, Mohammed MM, Bryant T, Kitteringham L, Pearce N, Abu Hilal M. "Stretching the limits of laparoscopic surgery": two-stage laparoscopic liver resection. Journal of laparoendoscopic & advanced surgical techniques. Part A. 2010;20:51-4.

• De Silva AN, Scibelli T, Itobi E, Austin P, Abu-Hilal M, Wootton SA, Stroud MA. Improving peri-operative fluid management in a large teaching hospital: pragmatic studies on the effects of changing practice. Proc Nutr Soc. 2010;69:499-507.

• Abu-Hilal M, Hemandas AK, McPhail M, Jain G, Panagiotopoulou I, Scibelli T, Johnson CD, Pearce NW. A comparative analysis of safety and efficacy of different methods of tube placement for enteral feeding following major pancreatic resection. A non-randomized study. JOP. 2010;11:8-13. • Abu Hilal M, Underwood T, Zuccaro M, Primrose J, Pearce N. Short- and medium-term results of totally laparoscopic resection for colorectal liver metastases. Br J Surg. 2010;97:927-33.

• Abu Hilal M, Underwood T, Taylor MG, Hamdan K, Elberm H, Pearce NW. Bleeding and hemostasis in laparoscopic liver surgery. Surg Endosc. 2010;24:572-7.

• McPhail MJ, Scibelli T, Abdelaziz M, Titi A, Pearce NW, Abu Hilal M. Laparoscopic versus open left lateral hepatectomy. Expert Rev Gastroenterol Hepatol. 2009;3:345-51.

• Al-Mukhtar A, Wong VK, Malik HZ, Abu-Hilal M, Denton M, Wilcox M, Lodge JP, Toogood GJ, Prasad KR. A simple prophylaxis regimen for MRSA: its impact on the incidence of infection in patients undergoing liver resection. Annals of the Royal College of Surgeons of England. 2009;91:35-8.

• Abu Hilal M, McPhail MJ, Zeidan BA, Jones CE, Johnson CD, Pearce NW. Aggressive multi-visceral pancreatic resections for locally advanced neuroendocrine tumours. Is it worth it? JOP. 2009;10:276-9.

• Abu Hilal M, Malik HZ, Hamilton-Burke W, Verbeke C, Menon KV. Modified Cattell's pancreaticojejunostomy, buttressing for soft pancreases and an isolated biliopancreatic loop are safety measurements that improve outcome after pancreaticoduodenectomy: a pilot study. HPB (Oxford). 2009;11:154-60.

• Abu Hilal M, Jain G, Kasasbeh F, Zuccaro M, Elberm H. Laparoscopic distal pancreatectomy: critical analysis of preliminary experience from a tertiary referral centre. Surg Endosc. 2009;23:2743-7.

• Abu Hilal M, Harb A, Zeidan B, Steadman B, Primrose JN, Pearce NW. Hepatic splenosis mimicking HCC in a patient with hepatitis C liver cirrhosis and mildly raised alpha feto protein; the important role of explorative laparoscopy. World J Surg Oncol. 2009;7:1.

• Young AL, Prasad KR, Adair R, Abu Hilal M, Guthrie JA, Lodge JP. Portal vein arterialization as a salvage procedure during left hepatic trisectionectomy for hilar cholangiocarcinoma. J Am Coll Surg. 2008;207:e1-6.

• Hemandas AK, Jain G, Fong F, Stedman B, Jaynes E, Abu Hilal M. Feasibility of laparoscopic distal spleno-pancreatectomy following previous necrosectomy. A case report. JOP. 2008;9:644-8.

• Dabbas N, Abdelaziz M, Hamdan K, Stedman B, Abu Hilal M. Gallstone-induced perforation of the common bile duct in pregnancy. HPB Surg. 2008;2008:174202.

• Casaril A, Abu Hilal M, Harb A, Campagnaro T, Mansueto G, Nicoli N. The safety of radiofrequency thermal ablation in the treatment of liver malignancies. Eur J Surg Oncol. 2008;34:668-72.

• Abu-Hilal M, Primrose JN, Casaril A, McPhail MJ, Pearce NW, Nicoli N. Surgical resection versus radiofrequency ablation in the treatment of small unifocal hepatocellular carcinoma. J Gastrointest Surg. 2008;12:1521-6.

• Abu-Hilal M, Abu-Hilal M, McPhail MJ, Zeidan B, Bryant T, Bateman A, Johnson CD. Acute pancreatitis as the first presentation of Wegener's granulomatosis. JOP. 2008;9:300-4.

• Abu Hilal M, Pearce NW. Laparoscopic left lateral liver sectionectomy: a safe, efficient, reproducible technique. Dig Surg. 2008;25:305-8.

• Abu Hilal M, McPhail MJ, Zeidan B, Zeidan S, Hallam MJ, Armstrong T, Primrose JN, Pearce NW. Laparoscopic versus open left lateral hepatic sectionectomy: A comparative study. Eur J Surg Oncol. 2008;34:1285-8.

• Abu Hilal M, Lodge JP. Pushing back the frontiers of resectability in liver cancer surgery. Eur J Surg Oncol. 2008;34:272-80.

• Abu Hilal M, Armstrong T. The impact of obesity on the course and outcome of acute pancreatitis. Obes Surg. 2008;18:326-8.

• Young AL, Malik HZ, Abu-Hilal M, Guthrie JA, Wyatt J, Prasad KR, Toogood GJ, Lodge JP. Large hepatocellular carcinoma: time to stop preoperative biopsy. J Am Coll Surg. 2007;205:453-62.

• Abu-Hilal M, Vanden Bossche M, Bailey IS, Harb A, Sutherland R, Sansome AJ, Byrne JP. A two-consultant approach is a safe and efficient strategy to adopt during the learning curve for laparoscopic Roux-en-Y gastric bypass: our results in the first 100 procedures. Obes Surg. 2007;17:742-6.

• Abu Hilal M, Ung CT, Westlake S, Johnson CD. Carboxypeptidase-B activation peptide, a marker of pancreatic acinar injury, but not L-selectin, a marker of neutrophil activation, predicts severity of acute pancreatitis. J Gastroenterol Hepatol. 2007;22:349-54.

• Abu Hilal M, Hallam MJ, Zeidan BA, Pearce NW. Management of a ruptured pseudoaneurysm of common hepatic artery following pancreaticoduodenectomy. TheScientificWorldJournal. 2007;7:1658.

• Zeidan BA, Abu Hilal M, Al-Gholmy M, El-Mahallawi H, Pearce NW, Primrose JN. Adenoid Cystic Carcinoma of the lacrimal gland metastasising to the liver: report of a case. World J Surg Oncol. 2006;4:66.

• McPhail MJ, Abu-Hilal M, Johnson CD. A meta-analysis comparing suprapubic and transurethral catheterization for bladder drainage after abdominal surgery. Br J Surg. 2006;93:1038-44.

• Abu-Hilal M, Salvia R, Casaril A, Pearce NW, Bassi C, Capelli P, Nicoli N. Obstructive chronic pancreatitis and/or intraductal papillary mucinous neoplasms (IPMNs): a 21-year long case report. JOP. 2006;7:218-21.

• Abu-Hilal M, Morgan EC, Lewis G, McPhail M, Malik HZ, Hocken D. What makes a good doctor in the 21st century? A qualitative study. Br J Hosp Med (Lond). 2006;67:375-7.

• Abu-Hilal M, McPhail MJ, Marchand L, Johnson CD. Malondialdehyde and superoxide dismutase as potential markers of severity in acute pancreatitis. JOP. 2006;7:185-92.

• Valerio A, Basso D, Fogar P, Falconi M, Greco E, Bassi C, Seraglia R, Abu-Hilal M, Navaglia F, Zambon CF, Gallo N, Falda A, Pedrazzoli S, Plebani M. Maldi-TOF analysis of portal sera of pancreatic cancer patients: identification of diabetogenic and antidiabetogenic peptides. Clin Chim Acta. 2004;343:119-27.

• Nicoli N, Casaril A, Mangiante G, Ciola M, Abu Hilal M, Marchiori L. Surgical treatment for liver metastases from colorectal carcinoma: results of 228 patients. Hepatogastroenterology. 2004;51:1810-4.

• Nicoli N, Casaril A, Abu Hilal M, Mangiante G, Marchiori L, Ciola M, Invernizzi L, Campagnaro T, Mansueto G. A case of rapid intrahepatic dissemination of hepatocellular carcinoma after radiofrequency thermal ablation. American journal of surgery. 2004;188:165-7.

• Johnson CD, Abu-Hilal M. Persistent organ failure during the first week as a marker of fatal outcome in acute pancreatitis. Gut. 2004;53:1340.

• Falconi M, Abu Hilal M, Salvia R, Sartori N, Bassi C, Pederzoli P. Prophylactic pylorus-preserving gastric transposition in unresectable carcinoma of the pancreatic head. American journal of surgery. 2004;187:564-6.

• Casaril A, Abu-Hilal M, Ciola M, Invernizzi L, Campagnaro T, Nicoli N. One death after radiofrequency thermal ablation for hepatocellular carcinoma in a cirrhotic patient. Surgery. 2003;133:598.

• Bassi C, Falconi M, Tihany T, Salvia R, Valerio A, Caldiron E, Abu Hilal M, Flautner LE, Pederzoli P. Resection in chronic pancreatitis: anastomosis with the jejunum or with the stomach? Ann Ital Chir. 2000;71:51-5.